Genomic changes associated with adaptation to arid environments in cactophilic Drosophila species
نویسندگان
چکیده
منابع مشابه
Genomics of Ecological Adaptation in Cactophilic Drosophila
Cactophilic Drosophila species provide a valuable model to study gene-environment interactions and ecological adaptation. Drosophila buzzatii and Drosophila mojavensis are two cactophilic species that belong to the repleta group, but have very different geographical distributions and primary host plants. To investigate the genomic basis of ecological adaptation, we sequenced the genome and deve...
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Drosophila mojavensis and Drosophila arizonae are species of cactophilic flies that share a recent duplication of the alcohol dehydrogenase (Adh) locus. One paralog (Adh-2) is expressed in adult tissues and the other (Adh-1) in larvae and ovaries. Enzyme activity measurements of the ADH-2 amino acid polymorphism in D. mojavensis suggest that the Fast allozyme allele has a higher activity on 2-p...
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Motivation Ebola viruses are not pathogenic but can be adapted to replicate and cause disease in rodents. Here, we used a structural bioinformatics approach to analyze the mutations associated with Ebola virus adaptation to rodents to elucidate the determinants of host-specific Ebola virus pathogenicity. Results We identified 33 different mutations associated with Ebola virus adaptation to ro...
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We report genomes of two species of cactophilic Drosophila: Drosophila arizonae and D. navojoa These two are the closest relatives of D. mojavensis, forming the D. mojavensis cluster. D. mojavensis and D. arizonae diverged from D. navojoa ∼5.8 Mya, while the split between D. arizonae and D. mojavensis is more recent, at 1.5 Mya. Together the three genomes provide opportunities to examine genomi...
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Crassulacean acid metabolism (CAM) is an important elaboration of photosynthetic carbon fixation that allows chloroplast-containing cells to fix CO2 initially at night using phosphoenolpyruvate carboxylase (PEPC) in the cytosol. This leads to the formation of C4 organic acids (usually malate), which are stored in the vacuole. Subsequent daytime decarboxylation of these organic acids behind clos...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2019
ISSN: 1471-2164
DOI: 10.1186/s12864-018-5413-3